مجلة النيلين الطبية
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Item The clinical importance of anti-CCP in early diagnosis of Sudanese patients with rheumatoid arthritis(جامعة النيلين - مركز النيلين الطبي, 2015-11) Ahmed BoladAbstract Background: Rheumatoid Arthritis (RA) is a systemic inflammatory autoimmune disorder; it is the most common inflammatory arthritis in the world. The early diagnosis and effective treatment of rheumatoid arthritis (RA) can improve the clinical outcome of the disease. Recently, anti-Cyclic- Citrullinated protein antibodies (Anti-CCP) are found to be more specific to RA arthritis although in the early stages when the arthritis is undifferentiated. The objective of this study was to determine the clinical importance and the prevalence of anti-CCP in early diagnosis of Sudanese patients with RA. Methodology This work was a cross-sectional study conducted at Al Ribat teaching hospital (from June 2012 to ? 2014). The study sample included 56 Sudanese patients, known patients of RA who fulfilled the ACR criteria. Demographic and clinical data were collected by questionnaires. All patients and controls sera were investigated for anti-CPP by enzyme linked immunosorbent assay (ELISA). Results The mean age of RA patients in this study was 46.0 (±11.7) years. The control group consisted of 56 Sudanese apparently healthy subjects, 27 (48%) of them were female with mean age of 37 ±17.2years. The anti-CCP antibodies were detected in 60.7% of cases, and in two (3.6%) of the control group. The sensitivity of anti-CCP was 60.7% and specificity of 96.4%. Anti-CCP test has a maximum proportionate reduction in uncertainty (PRU) of 94% for a positive result and 59% for a negative result. Conclusions Anti-CCP antibody has a higher diagnostic specificity and positive predictive value than rheumatoid factor; however its sensitivity was low. The consent of each patient was obtained prior to commencement of data collection.Item THE PREVELANCE OF HELICOBACTER PYLORI AMONG PATIENTS WITH CHRONIC IDOPATHIC URTICARIA(مركز النيلين الطبي, 2015) Sheema Mohsin Mustafa; Ahmed BoladLiterature review: Helicobacter pylori was first isolated by Warren and Marshall (Warren et al., 1983) in 1982 it was linked with chronic antral gastritis and peptic ulceration, at first they named the bacterium as Campylobacter pyloridis, later on it was renamed as Helicobacter pylori (Warren et al. 1984). The genus Helicobacter belongs to the subdivision of the Proteobacteria, order Campylobacterales, family Helicobacter-aceae. The genus Helicobacter consists of over 20 recognized species (Fox, 2002). Members of the genus Helicobacter are all microaerophilic organisms and in most cases are catalase and oxidase positive, and many but not all species are also ureases positive. Helicobacter species can be subdivided into two major lineages, the gastric Helicobacter species and the enterohepatic (nongastric) Helicobacter species. Both groups demonstrate a high level of organ specificity, such that gastric helicobacters in general are unable to colonize the intestine or liver, and vice-versa.Item Assessment of Nurse’s Competences during Emergency Management of patients with Acute Myocardial Infarction at critical care units and emergency department at Public Teaching Hospitals in Khartoum State (2013(جامعة النيلين- مركز النيلين الطبي, 2013) Hassanat Elbashir Mohamed Mustafa1; Mustafa Nimeiri; Ahmed Bolad; Siddig Khalil1Item Operational Research from Theory to Practice October 2011(جامعة النيلين- مركز النيلين الطبي, 2013) Mustafa Khidir Mustafa Elnimeiri; Ahmed BoladItem Prevalence of Schistosomiasis among School Children-South Kordofan State(جامعة النيلين- مركز النيلين الطبي, 2012) Mustafa Khidir Mustafa Elnimeiri; Ahmed BoladItem Clarithromycin-Resistant Helicobacter Pylori Strains among Dyspeptic Patients in Sudan(جامعة النيلين- مركز النيلين الطبي, 2012) Nazar Abdalazeem; Hassan Abdul-Aziz; Adam Ahmed Adam; Waleed Hussein Omer; Ahmed BoladItem Family and Community Support of TB Patients -Jebel Awleyah Locality-Khartoum Sudan -2011(جامعة النيلين, 2012) Mustafa Khidir Mustafa Elnimeiri; Ahmed BoladFamily and community support are always considered as essential factors need to facilitate coping of the patients with their disease and its outcome. In Sudan the family and ties are still firm. However family and community support for TB patients may not always be encountered to the same extent especially among urban populations. The design was facility-based descriptive. The study was conducted in Gebel Awleyah Locality, which is geographically located in the South of the National Capital of Sudan. The study population was composed of 348 TB patients (pulmonary and extra-pulmonary) in the TBMUs receiving DOT in the intensive phase. A Standardized pre-coded and pre tested administered questionnaire was used for data collection from the TB patients. 99% of the TB patients were supported by their families as they became sick. The family support was expressed in accompanying to the TBMU (96%) and in provision of extra food (99%). The family support in cash was encountered for about 73% of the TB patients. About 31% of the TB patients were supported by the community and 69% of them were not supported. For those TB patients, who were subjected to community support, were mainly supported by their neighbors (98%). The TB patients of both genders were supported by their families mainly by their bothers. The family support was marked in accompanying to the TBMUs and provision of extra food.