مجلة المختبرات الطبية - 2016 - 1 - 1
Permanent URI for this collectionhttps://repository.neelain.edu.sd/handle/123456789/3113
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Item Assessment of Trace Elements, Total White Blood Cells and Platelets Count in Pregnant Ladies with Preeclampsia in Sudan(Al Neelain University-Faculty of Medical Laboratory Sciences, 2016-02) Akram Elkhair Noor Eldaem; Salah Ismael; Elfadil AL ObeidOmerPreeclampsia is a multisystem disorder of pregnancy, which complicates pregnancy. Maternal mortality with pre-eclampsia/eclampsia in Sudan is ascertained and accounts for 4.2% of the obstetric complications in Sudan. Despite decades of research into the condition, predicting which women are at increased risk of developing preeclampsia remains problematic and we did this study to detect the role of some elements and to correlate them with Preeclampsia. Pregnant ladies with preeclampsia were selected as cases, and age matched with normal pregnant ladies as controls. Venous blood samples were collected from every patients and controls. Trace elements, copper, zinc, and iron were measured. Total white blood cells and platelets were counted also. Levels of copper and zinc were low in patients while they were normal in controls. Iron was normal, total white blood cells were high in patients and platelets were low. The reduction in serum levels of zinc and copper during pregnancy might be possible contributor in etiology of pre-eclampsia.Item Assessment of Preeclampsia Multiple Biomarkers in Sudan(Al Neelain University-Faculty of Medical Laboratory Sciences, 2016-02) Akram Elkhair Noor Eldaem; Salah Ismael; Elfadil AL ObeidOmerPreeclampsia is a multisystem disorder of pregnancy, which complicates pregnancy. It is a major cause of maternal morbidity and mortality worldwide. Although pre-eclampsia is an important cause of maternal and fetal morbidity and mortality, its aetiology is still under investigation. The aim of the present study was to investigate biochemical markers in preeclampsia predictions. We focused in this study on organs functions and analysis of different analysts, and salts in the preeclamptic females to gather which factors could influence or predict the preeclampsia. Pregnant women were selected, venous blood samples were collected from every patients and controls. Liver and renal function tests were measured for urea, creatinine, uric acid, calcium, magnesium, phosphorus, total protein, albumin, aspartate aminotransferase (AST), alanine aminotransferase (ALT), total and direct serum bilirubin, sodium and potassium. Urea, creatinine, sodium, potassium, total protein, albumin, total and direct serum bilirubin concentrations were normal in patients and controls. Uric acid, magnesium, aspartate aminotransferase, alanine aminotransferase were found to be markedly increased in patients while calcium and phosphorus were decreased. These results indicate that the elevation of uric acid, magnesium, aspartate aminotransferase enzyme, alanine aminotransferase enzyme and the reduction in serum levels of calcium during pregnancy might be possible contributors in etiology of pre-eclampsia.