مجلة المختبرات الطبية 2018 - 1 - 1
Permanent URI for this collectionhttps://repository.neelain.edu.sd/handle/123456789/14291
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Item Seroprevalence of the West Nile Virus among blood donors attending to the Central Blood Bank at Khartoum State, Sudan(2018) Mohammed Sherif Yousif Mohammed; Mustafa EM Yassin; Abbas Bakhit Mohammed RahamaBackground: The West Nile Virus (WNV) is an arthropod-borne (arbo) flavivirus, which causes different forms of infection among humans. West Nile virus may also be transmitted by blood transfusion. Blood donors who donated at the central blood bank were not investigated for the presence of the WNV in their blood in spite of the fact that many blood donors live in areas containing mosquitoes and they may carry the WNV in their blood. The aim of this study was to detect the seroprevalence of WNV among blood donors in Khartoum state, during Oct. 2016 by using conventional ELISA methods (Euro immune, Germany). Materials and Methods: In this cross sectional descriptive study, Ninety-one blood donors were included. The study population included male Blood donors with ages ranging from 18 up to 57 (mean 31.5) years old. 5 ml of blood sample from each blood donor was collected and then serum was obtained from each sample. These sera were tested for antibodies (IgG, IgM) against WNV by an ELISA test using Euro immune ELISA kits according to the manufacturer instructions. Results: In the current study, out of 91 blood donors screened for WNV IgG, and IgM antibodies during Oct 2016 by using ELISA, 58 (63.7 %) were positive. Fifty-two (57.1%) of them were found positive for WNV IgG antibodies while 14 (15.4%) were positive for W