مؤتمر الدراسات العليا السنوي 06

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    Rheumatoid arthritis and anti-CCP
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Yousif Osman; Shaaban Khudair; Ahmed Bolad
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    Cigarette Smoking & Oral Hygiene Measure among Chronic Periodontitis Patients in Khartoum Dental Hospital
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Wafaa Mohammed Abdelwahab Eltazi
    Background information: Periodontal diseases comprise a group of inflammatory conditions of the supporting structures of teeth, including the gingiva, periodontal ligament and alveolar bone. Cigarette smoking is a major systemic risk factor for periodontal diseases. Microbial dental plaque biofilms are the principal etiological factor of periodontitis. Aim of study: Evaluate the effect of cigarette smoking on the level of oral hygiene. Materials and methods: Smoking status was assessed by Self reported questionnaire. The level of oral hygiene was assessed by plaque index (PI) Silness and Loe (1964) &Sextants were used according to FDI (WHO 1983).Result:70.3% of patients with poor plaque indices (N =239) were smokers. Alternatively, all patients with good and fair plaque indices (N =111) were non-smokers. Smokers risk of developing poor plaque index is more than twice that of non-smokers (RR =2.56).Conclusion: Smokers showed more plaque accumulation than non-smokers. Recommendation: There is an urgent need to start an intensive education program to the public on the negative health consequences of cigarette smoking.
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    Cigarette Smoking &Gingival Bleeding among Chronic Periodontitis Patients in Khartoum Dental Hospital
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Wafaa Mohammed Abdelwahab Eltazi
    Background information: Periodontal diseases comprise a group of inflammatory conditions of the supporting structures of teeth, including the gingiva, periodontal ligament and alveolar bone. Cigarette smoking is a major systemic risk factor for periodontal diseases. Microbial dental plaque biofilms are the principal etiological factor of periodontitis. Aim of study: Evaluate the effect of cigarette smoking on the level of oral hygiene. Materials and methods: Smoking status was assessed by Self reported questionnaire. The level of oral hygiene was assessed by plaque index (PI) Silness and Loe (1964) &Sextants were used according to FDI (WHO 1983).Result:70.3% of patients with poor plaque indices (N =239) were smokers. Alternatively, all patients with good and fair plaque indices (N =111) were non-smokers. Smokers risk of developing poor plaque index is more than twice that of non-smokers (RR =2.56).Conclusion: Smokers showed more plaque accumulation than non-smokers. Recommendation: There is an urgent need to start an intensive education program to the public on the negative health consequences of cigarette smoking.
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    Acceptability of Reproductive Health Information, Education and Communication printed materials- Khartoum and East Nile localities
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Soad Mohammed Abdulla Alnassri; Dr. Mustafa Elnimeiri
    The IEC messages must be acceptable to the target population. If communication material contains something offensive, is not believable, the audience will reject the message conveyed. The overall aim of the study was to assess the acceptability of reproductive health IEC printed materials. Materials and methods: A descriptive - cross sectional study was conducted in health facilities at Khartoum and East Nile localities at Khartoum State. The total number of mothers enrolled in this study mounted to 385 mothers. Data were collected using a standardized administered questionnaire to assess the acceptability of information, education and communication printed materials in reproductive health. SPSS version 16 was used to analyze the collected data
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    Comparison of Rheumatoid Factor and anti-Cyclic-Citrullinated protein antibodies for the Diagnosis of rheumatic arthritis in Khartoum, Sudan
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Shaaban Khudair; Mowahib Al Edressy; Mohammed Abbas; Ahmed Bolad
    Background: The objective of the current study was to determine the sensitivity and specificity of anti-Cyclic-Citrullinated protein antibodies (anti-CCP antibodies) as compared to that of Rheumatoid Factor (RF) in diagnosing patients with rheumatoid arthritis (RA) Methodology Fifty six samples were collected from Sudanese patients (46 females, 9 males) with rheumatic diseases who visited the rheumatology clinic ElRibat Hospital, Khartoum, Sudan. Titers of RF and anti-CCP antibodies of each patient were recorded. Sensitivity and specificity of the test were evaluated using ELISA as the gold standard method. Results The sensitivity of (RF) test (41/56) was 73.2% whereas the sensitivity of Anti CCP test (34/56) was 60.7%. The specificity of RF test (44/56) was 78.6%, whereas the specificity of Anti CCP test (54/56) was 96.4%. Conclusions The combination of anti-CCP and RF tests provides nearly 100% and thus could be helpful in the differential diagnosis of RA and other rheumatic diseases
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    The clinical importance of anti-CCP in early diagnosis of Sudanese patients with rheumatoid arthritis
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Yousif Osman; Shaaban Khudair; Ahmed Bolad
    Background: Rheumatoid Arthritis (RA) is a systemic inflammatory autoimmune disorder; it is the most common inflammatory arthritis in the world. The early diagnosis and effective treatment of rheumatoid arthritis (RA) can improve the clinical outcome of the disease. Recently, anti-Cyclic-Citrullinated protein antibodies (Anti-CCP) are found to be more specific to RA arthritis although in the early stages when the arthritis is undifferentiated. The objective of this study was to determine the clinical importance and the prevalence of anti-CCP in early diagnosis of Sudanese patients with RA. Methodology This work was a cross-sectional study conducted at Al Ribat teaching hospital (from June 2012 to ? 2014). The study sample included 56 Sudanese patients, known patients of RA who fulfilled the ACR criteria. Demographic and clinical data were collected by questionnaires. All patients and controls sera were investigated for anti-CPP by enzyme linked immunosorbent assay (ELISA). Results The mean age of RA patients in this study was 46.0 (±11.7) years. The control group consisted of 56 Sudanese apparently healthy subjects, 27 (48%) of them were female with mean age of 37 ±17.2years. The anti-CCP antibodies were detected in 60.7% of cases, and in two (3.6%) of the control group. The sensitivity of anti-CCP was 60.7% and specificity of 96.4%. Anti-CCP test has a maximum proportionate reduction in uncertainty (PRU) of 94% for a positive result and 59% for a negative result. Conclusions Anti-CCP antibody has a higher diagnostic specificity and positive predictive value than rheumatoid factor; however its sensitivity was low.
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    Quality of nursing care for under-five children regarding management of dehydration
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Nadia Mamoun Amin; Prof: Abdelmageed Osman Musa
    Dehydration is one of the leading causes of mortality among under-five children worldwide and mainly in developing countries. In Sudan, 20% of under-five children die due to dehydration. Nursing is essential in the management of dehydration. The objective of this study was to assess the quality of nursing care which was received by under-five children who were primary diagnosed with dehydration Materials and methods: A total of 159 pediatric nurses were enrolled in this study. Data was collected by structured questionnaire and observational checklist and were analyzed by SPSS
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    The role of Solute carrier family 30 (zinc transporter), member 8, "SLC30A8" gene polymorphism in susceptibility to Type 2 Diabetes in selected Sudanese population
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Hadeel Ibrahim; Mohammed Salih; Mr. Amir Ibrahim; Hiba Salah-Eldin Mohamed
    Abstract: Background: SLC30A8 rs11558471 (26465A/G SLC30A8) is Single Nucleotide Polymorphism (SNP), which was found to be associated with Diabetes Type 2 in Han Chinese and European population and represents three other SNPS (rs3802177, rs13266634, rs11558471 ). Variation in SLC30A8 may affect zinc accumulation in insulin granules, affecting insulin stability, storage, or secretion. Higher total zinc intake may attenuate the glucose-raising effect of the rs11558471 SLC30A8 (zinc transporter) variant. Objective: To determine the role of 26465A/G SLC30A8 in susceptibility to T2D in selected Sudanese population
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    Molecular detection of Torqueteno virus in healthy blood donors in Khartoum-state, Sudan
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Ahmed M Alamin; Khalid A Enan; Isam M Elkhidir
    Abstract: Torgue teno virus (TTV) is a recently discovered virus with a high DNA prevalence in different populations. Its role in pathogenesis is uncertain. This study was conducted to determine the existence of Torgue teno virus DNA (TTV DNA), and the prevalence of (TTV), among blood donors in Khartoum State, and to generate preliminary rate of infection. The methods used in this present study were conventional PCR diagnostic methods, amplifying the untranslated region (UTR) of (TTV) in serum samples. The consensus primers used are T801 and T935, both primer are able to identify all the genotypes of this virus. 81 Sudanese blood donors, (volunteers) admitted to blood bank Soba Hospital, south of Khartoum were selected for this study. The ages of samples ranged from 18 to 60 years with the mean age of 39 years. Samples were collected throughout the period of October to November 2012. The results which are statistically analyzed show that there was No significant differences in DNA prevalence of (TTV) among blood donors (P>0.05) in their serum samples. The present study is one of first attempts to reports directly major infection rate of TTVDNA in blood donors in Khartoum state Sudan, and focus on the molecular diagnosis of TTV DNA. It revealed that TTV was circulating in Sudan among healthy blood donors. The results of present study demonstrated a high prevalence of TTV in blood donors in Khartoum State-Sudan. Further studies are required to determine prevalence of TTV in other groups and the role of TTV in the pathogenicity of acute and/or chronic liver disease. Key words: Torqueteno virus (TTV), blood donors, untranslated region (UTR), TTV DNA, PCR