Masters theses : Medical Laboratory Science

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Subject: search.filters.subject.CVD among patients

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    Plasma Levels of Chromium and Manganese among Newly Diagnosed CVD Patients in Khartoum State
    (Alneelain University, 2017-02) Bhaa El Dine AL Fadil Mohamed AL Nour
    Background: There are many diagnostic pathway to increase awareness of CVD among patients. This study was conducted to assess the trace elements especially (Cr, Mn) concentration in all type of newly diagnostic CVD patients, as cross sectional study to determine the impact of the heart disease. Methods: This study is a cross- sectional study conducted in Sudan Heart Center – AL- Shaab Teaching Hospital –Ahammed Gassem Teaching Hospital, at Khartoum state in Sudan during period of November 2016 to January 2017. Sixty newly diagnostic CVD patients were selected to participate in this study, 44 of them above 50 years and 16 below 50 years. And the trace elements (Cr,Mn) were measured by using AAS (Atom absorption spectrophotometer). Results: The mean levels of chromium and manganese in CVD patients comparison with Reference value revealed significance difference P-value (0.000, 0.000) respectively. The mean levels of (Cr,Mn) when compared between the two age group (<50, >50 years) observed significant difference P-value (0.006, 0.004) respectively. The mean levels of chromium and manganese in CVD smokers was found significantly increased when compared with non-smokers CVD patients. The mean levels of chromium and manganese in CVD diabetic patients was significantly increased when compared with non-diabetic CVD patients. The mean levels of chromium and manganese in CVD hypertensive patients was insignificantly increased when compared with non-hypertensive CVD patients. The mean levels of chromium and manganese in CVD obese patients was insignificantly increased when compared with non-obese CVD patients. As well as in Comparison between CVD alone patients as group and CVD with other risk factors (DM, HTN) the mean levels observed significantly increased in the second groups. Conclusions The trace elements (Cr,Mn) is significantly decreased among CVD patients without risk factors and significantly increased in patients with risk factors (DM, HTN, smoker and obesity).