Impact of Myopia on Macular Thickness: Anoptical Coherence TomographyStudy of Young Sudanese

Abstract

Aims: To investigate the changes in macular thickness of myopic eyes using spectral domain optical coherence tomography (OCT). Methods: A prospective cross-sectional study was perfomied in hundred young Sudanese patients (15-30 years) with myopia in period from June to December 2015 at Makkah Eye complex, Khartoum, Sudar1.Patients were divided into three groups according to their refractive error and axial length: low and medium myopia (LMM), high myopia (HM) and Super high myopia (SHM). A comprehensive ophthalmic examination were performed; including measurement of visual acuity, refraction, and axial length. Subjects with ophthalmic abnormalities were excluded. Thus, Carl Ziess OCT was used to evaluate total macular thickness, foveal thickness, parafoveal and perifoveal thickness and macular volume. The differences among experimental groups were analyzed by one-factor analysis of variance. However, associations between macular thickness and refractive error/axial length were analyzed by Pearson’s correlation analysis. Results: The study revealed that there was no significant difference in age among the three groups (p=0.278). The mean of refiactive error in the LMM, HM, and SI-IMwas -3.l1=l:1.20D, -7.49 il.03D and - l6.58i5.00D, respectively (p<0.001). The foveal thickness of the three groups was 236.38:t20.80|.1m, 245.43=l=29.55um and 258.93:t:32.38um,