Haematological values disorders among malaria-infected children attending the military hospital, in Khartoum state, in Sudan

Abstract

Abstract Introduction

Malaria is a major health problem and one of the major killers in paediatric population particularly in the developing world. High mortality is usually compounded by various haematological complications

Objective

This study determined the effect of malaria infection on haematological values amongst children

Method

fifty malaria-infected children, aged 2–15 years, and 50 age-matched uninfected children were studied during march –july 2017 the diagnosis of malaria was confirmed by thick and thin film stained with giemsa staining for malaria parasite and complete blood counts (cbcs) were performed using an automated sysmex machine

Results: The study shows Haematological values in malaria-infected and control subjects which presented there is significant difference between the mean of haemoglobin concentration , platelet count, neutrophil , and lymphocyte in study group patients and control group (12.45±1.47) versus (11.95±1.12), (104.88±32.74)versus (381.00±71.26), (50.78±17.87) versus( 38.28±11.87) , (36.34±16.19) versus (48.66±12.65) respectively(p value =0.056 ,0.000, 0.000 ,0.000 respectively ). And shows there is no statistical significant difference between the mean of white blood cell ,red blood cell ,haematocrite ,monocyte ,and esinophil( p=0.187, 0.725, 0.316, 0.928, 0.824 respectively) there is no statistical significant difference in the mean level of Haematological values between male and female in the study group patients. there is statistical significant difference between the mean of white blood cell ,platelet ,lymphocyte , esinophil , and degree of hyperparasitemia in study group (p=0.034, 0.000, 0.011, 0.044) respectively . there is no statistical significant difference in the mean level of red blood cell , hemoglobin, heamatocrite , nutrophil, monocyte, and degree of hyperparasitemia in study group. Conclusion

changes in haematological values in malaria-infected children are associated with lymphopenia and neutrophilia and thrombocytopaenia irrespective of their sex. it is recommended that platelet count be determined as it could