Assessment of Cholesterol Profile among Sudanese Tobacco Smoking Females in ALGezira State

Abstract

Background: Cigarette smoking is one of the leading causes of preventable morbidity and mortality that usually starts in adolescence and continues into adult life. In the developing world, tobacco consumption is rising especially among youth. The tobacco smoking is could lead to premature development of Cardio vascular disease CAD and abnormal levels of risk factors such as serum lipid and lipoprotein levels, hypertension, and smoking are related to the earliest stages of atherosclerotic CAD. Objective: the aim of this study was to assess cholesterol profile among tobacco smoking females in ALgezira State. Materials and methods: In this case control study conducted in, Gezira state. 100 subjects were involved. 50female smokers with a mean age of 34 years and control group was comprised of Fifty healthy individual with a mean age of 34 years.Serum level of lipid profile (Total cholesterol TCH, Low density lipoprotein LDL and High density lipoprotein HDLmeasured by colorimetric method in fully Automated Biochemistry Analyzer (Mindary BS-200automatic chemistry analyzer) Results :results showed A significantly increased of serum Cholesterol, and Low density lipoprotein with significant decreased in serum High density lipoprotein level in female smokers as compared to non smokers and same results were found in smoker group with 5 cigarettes smoked per day while with increase duration of smoking the TC & LDL were increased, TG showed no difference while the HDL was decreased showing greater risk of these persons to atherosclerosis and coronary heart disease. Conclusion: There are significant increase of serum total cholesterol and low density lipoprotein and there is a significant decrease in high density lipoprotein in tobacco smoking femalesas compared to non smoker