Determination of Serum Chromium (Cr), lron (Fe), Copper (Cu), and Cobalt (Co) Levels and Hematological Parameters of People from Blue Nile State, (Engassana Mountains) and Khartoum State

Abstract

In the present study, determination of serum trace elements using Atomic Absorption Spectrophotometry and evaluation of hematological parameters using an Automated Hematology Analyzer in human blood samples of people from Blue Nile State (Bao and Jam areas) and Khartoum State were investigated. Serum elements, Chromium (Cr), Iron (Fe), Copper (Cu) and Cobalt (Co) concentrations and hematological values, hemoglobin (Hb), hematocrit (I-lct), red blood cell counts (RBC), white blood cell counts (WBCs), mean corpuscular volume (MCV), mean cell hemoglobin concentration (MCHC) and mean corpuscular hemoglobin (MCH), concentrations were evaluated regarding sex and location. Chromium and Iron showed significant differences (P< 0.05) in the three different areas however, Iron values were found to be within the 1'10l'lTl8l ranges. Serum levels ofChromium in Jam area showed significant increase (P< 0.05). Copper and Cobalt revealed no significant variations (P>0.05) and the values were found to be in the nonnal reference ranges. Sex had no influence on Chromium, Copper and Cobalt but Iron values were higher in male than female however, the difference was not significant (P>0.05). The hematological values, WBC, RBC, Hb, PCV red cell indices and differential WBC counts showed significant differences (P>0.05) among the three different populations but all of them remained within the normal reference ranges. At the same time all of these values were found to be similar in Bao and Jam areas. The values among sex groups did not show significant differences except for hemoglobin, which was found to be higher in male groups.