Abstract
In this thesis we presented a quasispecies mathematical model for two com-
peting cell populations. We toke into account the dynamics of heterogeneous
tumor cell populations competing with healthy cells. We analyze a mathemat-
ical model of unstable tumor progression using the quasispecies framework to
define a minimal model incorporating the dynamics of competition between
healthy cells and a heterogeneous population of cancer cell phenotypes involv-
ing changes in replication-related genes.
