Browsing by Author "Hiba Salah-Eldin Mohamed"

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    The role of Solute carrier family 30 (zinc transporter), member 8, "SLC30A8" gene polymorphism in susceptibility to Type 2 Diabetes in selected Sudanese population
    (جامعة النيلين - كلية الدراسات العليا, 2014-12-22) Hadeel Ibrahim; Mohammed Salih; Mr. Amir Ibrahim; Hiba Salah-Eldin Mohamed
    Abstract: Background: SLC30A8 rs11558471 (26465A/G SLC30A8) is Single Nucleotide Polymorphism (SNP), which was found to be associated with Diabetes Type 2 in Han Chinese and European population and represents three other SNPS (rs3802177, rs13266634, rs11558471 ). Variation in SLC30A8 may affect zinc accumulation in insulin granules, affecting insulin stability, storage, or secretion. Higher total zinc intake may attenuate the glucose-raising effect of the rs11558471 SLC30A8 (zinc transporter) variant. Objective: To determine the role of 26465A/G SLC30A8 in susceptibility to T2D in selected Sudanese population
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    The role of Solute carrier family 30 (zinc transporter), member 8, "SLC30A8" gene polymorphism in susceptibility to Type 2 Diabetes in selected Sudanese population
    (جامعة النيلين, 2010) Hadeel Ibrahim; Mohammed Salih; Mr. Amir Ibrahim; Hiba Salah-Eldin Mohamed
    Background: SLC30A8 rs11558471 (26465A/G SLC30A8) is Single Nucleotide Polymorphism (SNP), which was found to be associated with Diabetes Type 2 in Han Chinese and European population and represents three other SNPS (rs3802177, rs13266634, rs11558471 ). Variation in SLC30A8 may affect zinc accumulation in insulin granules, affecting insulin stability, storage, or secretion. Higher total zinc intake may attenuate the glucose-raising effect of the rs11558471 SLC30A8 (zinc transporter) variant. Objective: To determine the role of 26465A/G SLC30A8 in susceptibility to T2D in selected Sudanese population