Safa Siddig Alhag Ali2017-10-292017-10-292016http://hdl.handle.net/123456789/6484Abstract Substitution reactions of cyano(ligand)cobaloxime with N- donor ligands alanine, pyridine, aniline, and with The S- donor ligand Thiosemi-carbazid have been studied as incoming nucleophiles. These cyano(Ligand)cobaloximes have been synthesized and characterized on the basis of elemental analysis, IR, 1H and 13C NMR spectroscopy. The frequency changes in the IR spectra and shifts in the NMR were explained on the basis of back-donation of electrons from metal to the ligand and the basicity of the ligand. The characteristic absorption band of ν(C=N) in cyanocobaloximes and shifting to higher wave numbers as the donating power of the base ligand increases. Anti-bacterial activity of the complexes have been screened in vitro against the microorganisms Salmonella, it showed that these complexes can be used as drugs for the near future.Antibacterial Activity.Thesis