Red blood cell alloimmunization among Sudanese homozygous sickle cell disease patients

Abstract

Background: Transfusion of RBCs is a major therapeutic option for anemia in homozygous

SCD. Numerous studies conducted in the world to determine the frequency of

alloimmunization in SCD patients, but there are no studies conducted in Sudan in open

literature, to our knowledge. The objective of this study was to assess the incidence of RBC

alloimmunization in SCD HbSS patients in Sudan. Methods: This study was conducted in

Omdurman between August 2011-Aril 2012, in 100 SCD HbSS patients of age between 6 ...