Antibodies to the Plasmodiumfalciparum antigen Pf332 cooperated with human monocytes inhibit parasitegrowth by inducing intraerythrocytic abnormal parasite forms in vitro

Abstract

IntraerythrocyticPlasmodium parasite proliferation istightly related to disease seriousness.

Intraerythrocytic parasite developmentis fundamental to the proliferation of the malaria

parasite which is affectedby many factors. Antibodies inhibiting intraerythrocytic parasite

growth ordevelopment have been long indicated in protective immune mechanisms,

particularly in cooperation with human monocytes. Here, we show that the developmentP.

falciparum intraerythrocyticparasite was significantly disturbed by antibodies reactive with ...