The use of impregnated curtains does not affect antibody responses against Plasmodium falciparum and complexity of infecting parasite populations in children from Burkina Faso

Abstract

In Burkina Faso, where malaria is hyper-endemic and transmission intensity is very high, the

majority of malaria-related morbidity and mortality occurs in children less than 5 years of

age. A control measure such as the use of insecticide-treated curtains (ITC) significantly

reduces transmission of malaria infection. Concerns remain whether reduced transmission

intensity may lead to a delay in the development of immunity in younger children and even

to a partial loss of already acquired immunity. In this study, the levels of P. falciparum- ...