Detection of Autoimmune Hemolytic Anemia In Women With Breast Cancer In Khartoum, Sudan 2022
Date
2022-11
Journal Title
Journal ISSN
Volume Title
Publisher
Al-Neelain University
Abstract
Abstract
Introduction: Breast cancer is the second most common solid cancer in women, worldwide. Several etiologic factors may cause autoimmune hemolytic anemia in a patient with solid cancer. Autoimmune hemolytic anemia is a prevalent complication in patients with solid cancer.
Aim: This study aimed to detect the autoimmune hemolytic anemia in women with breast cancer
Materials & Methods: In this cross-sectional study, Whole blood samples were collected from 60 female patients with breast cancer in EDTA blood containers. Complete blood count, thin blood films, reticulocyte count and comb's test were conducted. Data obtained was analyzed by means of statistical package of social science (SPSS).
Results: A total of 60 Sudanese breast cancer female patients were enrolled in this study , their mean age was 45.9 years and the duration mean was 1.8 year , the majority type of breast cancer was Infiltrating ductal carcinoma 96.7% Fell in three stages I , II , III with the majority of stage II 63.3% , Blood films’ comments were conducted through direct examination of stained blood films Red cell appearance included normocytic normochromic picture which presented among 83.3% of patients, hypochromia among 16.7% , white cell appearance include neutrophilia among 1.7%, Lymphocytosis among 1.7% and Monocytosis among 15% of patients and Platelet were increased among 6.7% , analyzed for the presence of anti-human globulin were negative result 100%
Conclusion: In this study patients involved are negative for direct antiglobulin test.
ملخص الدراسة
مقدمة:
سرطان الثدي هو ثاني أكثر أنواع السرطانات الصلبة شيوعًا بين النساء في جميع أنحاء العالم. قد تسبب العديد من العوامل فقر الدم الانحلالي المناعي الذاتي في المرضى المصابون بالسرطان الصلب ولأن فقر الدم الانحلالي بالمناعة الذاتية هو من المضاعفات السائدة المرتبطه بعدد من السرطانات الصلبة مثل سرطان الرئة وسرطان المبيض .
الهدف : هدفت هذه الدراسة إلى البحث في وجود فقر الدم الانحلالي بالمناعة الذاتية بين النساء المريضات بسرطان الثدي.
المواد والطرق:
تم جمع عينات دم كاملة من 60 مريضًة مصابًة بسرطان الثدي في أنابيب حمض إيثيلين أميني تتراسيتيك. تم إجراء تعداد الدم الكامل وأغشية الدم الرقيقة وعدد الخلايا الشبكية واختبار كومب. تم تحليل البيانات التي تم الحصول عليها عن طريق الحزمة الإحصائية للعلوم الاجتماعية.
Description
A dissertation submitted in partial fulfillment for the requirement of an M.Sc degree in Hematology & Immunology hematology
Keywords
Breast cancer, Hemolytic Anemia
